I know that the doco says you have to run a "family" of components, but I'll note that my 2x11 mashup is working great on my C'dale Scalpel

Shifters: (2016) SRAM X0 front, (2017) X01 rear
Front Derailleur: stock Shimano XT M8000
Rear Derailleur: stock SRAM GX, 11-speed long cage
Cassette: SRAM XG-1199 10-42
Chain: KMC X11SL
Cranks: stock Cannondale forged Si, 36/26 CNC Rings (FSA)