The Frequency i23 is designed specifically to work with the TCS tires with ease. The "old" Flow seems to work well with most Tubeless Ready tires IME. Not sure how the new Flow EX will though as it uses the 2nd generation BST which is catered more for running standard tires.
I'd go TCS all the way as it's a guaranteed success.
Former bicycle mechanic for 8 years, current soil scientist.