So I have a 2011 Focus Mares stock wheelset I plan to keep with some Vittorias just for wet/mud conditions.

However I just got off a friend a new pair of Vuelta Corsa SLR wheels.
The reported profile on Nashbar is 22mm. On vuelta site its
*Wheelset Rims: 27mm medium-V 6066 aluminum alloy welded clincher*

I want to use the Vuelta wheelset on pavement almost exclusively , and while I know the frame has clearance I dont know if my currently unused Marathon Supreme plus 700X35 would be an issue with these rims.
I love these tires and want to put them to use but also don't want to have wheel failures or safety concerns because of it.
Any input ?